Quant f(x) platform

The Leader in Reaping the Value of Tissue Information
TissueInformatics pioneered the segment of bioinformatics focused on delivering tissue information. Tissue information provides a context for interpreting molecular and cellular activity, reveals structural and functional information at the point where disease diagnosis is made, and bridges the current gap in quantitative biological data between the microscopic level and total systems.

Continuum of Bioinformatics
Genomics Digital Cell TissueInformatics Visible Human
DNA Data Cellular Data Tissue Information:
Where Diagnosis Occurs
Organism Information

In the Netherlands embryoadoptie have not been permitted. Similar to the quantitative data generated at the molecular level by micro arrays and sequencers, quantitative data is derived from tissue samples using "machine vision," computerized, automated processes that both identify and quantify the essential structural characteristics and elements within tissues. TissueInformatics bridges the gap in bioinformatics by developing customized Tissue Information Solutions powered by the quantitative data of machine vision analysis. Ægdonor ægdonor udført, ingen befrugtning eller deli.

Providing Comprehensive Tissue Information Solutions™
TissueInformatics is the only company providing Tissue Information Solutions, a comprehensive set of tools to quickly and easily capture, analyze, search and mine the rich data present in any tissue. Über das eizellspende-Programm erzählt.

Our Tissue Information Solutions:
enable the rapid reliable comparison of tissues,
provide a new platform for understanding disease and drug effects, and
can be further enriched when correlated with genomic, proteomic and other biological data.
     


Taking Tissue Information to the Next Power

Our customized Tissue Information Solutions are based upon TissueInformatics' unique Quantf(x) technology platform, which is applied to automatically identify and quantify any feature ( ) of interest in a customer-defined tissue investigation ( x ).

High-resolution tissue images are analyzed using the Quantf(x) platform of proprietary algorithms that extract and automatically analyze tissue features based upon essential elements of shape, color (from staining or microscopy) and architecture (i.e. size, volume, distance, etc.). The images and their corresponding quantitative information are stored in a flexible data structure than can simplify reporting and be queried and mined for correlation with other relevant data. Using Quantf(x), TissueInformatics can automate the identification and the quantitative measurement of any structural or molecular element within tissue that can be made visible. Both the digital image and data derived through the application of Quantf(x) is stored in a flexible data format to allow further analysis and correlation with other biological information.
 

  Quantf(x)™ Saves Time, Provides Accurate, Reproducible Results
TissueInformatics' Quantf(x) technology platform has already been applied to more than a dozen different types of tissues including liver, skin, muscle, cartilage, bone and others and is customizable to analyze any feature that can be made visible in any type of tissue.
 
 
 


The following example shows a Quantf(x) application to characterize the geometry of experimentally injured blood vessels. The process automates the analysis and archives the extracted information directly with the high-resolution images.

A Quantf(x) technology was developed to identify and quantify key structural features in vascular tissue to screen the effects of inhibitors of endothelial cell growth on vascular stenosis following experimental balloon angioplasty.

Previously, this type of analysis required 3 to 4 days to manually identify and process the structural data from 30 tissue slides. TissueInformatics' Quantf(x) technologies process and analyze 30 slides in a few hours with greater precision, resolution and reproducibility than the manual method.
 


The data derived from analyses powered by our Quantf(x) technologies is stored in flexible data formats. Analysis results can be imprinted directly on the specimen image for auditing purposes or data can be analyzed and correlated with other biological data set, output in spreadsheets, graphs or any other useful graphical format.

 
Download an information sheet about the Quantf(x) platform
     

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